Allah said:

[Yusufali 39:65] But it has already been revealed to thee,- as it was to those before thee,- “If thou wert to join (gods with Allah), truly fruitless will be thy work (in life), and thou wilt surely be in the ranks of those who lose (all spiritual good)”.

In Tafseer of Furat al-Kufi narrated from Abu Jafar (alaihi salam):

If you would make shirk in the wilayah of Ali, you would be surely be in the ranks of those who lose (all spiritual good)